research news

Learning from scorpions to control impulses

Scorpions can teach us a lot about the benefits of prolonging nerve impulses, and we might now be better students thanks to a study published in The Journal of General Physiology. The results could pave the way for easier identification of drugs that function similarly to scorpion venom, but with happier results for the recipient.

research news

Live broadcast from inside the nerve cell

Scientists estimate that our brain consists of about ten to one hundred billions of nerve cells. In order to fulfill their respective tasks as long as possible, these cells have to constantly control their internal proteins with regard to quality and functionality. Otherwise the proteins might clump together and thereby paralyze or even kill the cells. Once the cell recognizes a defect protein, this is marked for degradation and a kind of a molecular shredder, the so-called proteasome, chops it into pieces that are eventually recycled.

research news

Dragnet for epilepsy genes

An international team of scientists together with the University of Bonn Hospital have taken a new path in the research into causes of epilepsy: The researchers determined the networks of the active genes and, like a dragnet, looked for the "main perpetrators" using a computer model. In doing so, they discovered the molecule sestrin-3 as a central switch. In animal models, the scientists were able to demonstrate that inhibition of sestrin-3 leads to a reduction in seizures. The results are now being presented in the renowned journal "Nature Communications".

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