research news

Orphan receptor proteins deliver 2 knock-out punches to glioblastoma cells

Two related proteins exert a lethal double whammy effect against glioblastoma cells when activated with a small molecule, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

The scientists say when activated, one protein, called the short form, stops glioblastoma cells from replicating their DNA, and the other, called the long form, prevents cell division if the DNA has already been replicated, explains Rebecca Riggins, PhD, assistant professor of oncology at Georgetown Lombardi. The study was posted online Dec. 12 in the journal Cell Cycle.

research news

Bugs life: the nerve cells that make locusts ‘gang up’

A team of biologists has identified a set of nerve cells in desert locusts that bring about 'gang-like' gregarious behavior when they are forced into a crowd.

Dr. Swidbert Ott from the University of Leicester's Department of Biology, working with Dr. Steve Rogers at the University of Sydney, Australia, has published a study that reveals how newly identified nerve cells in locusts produce the neurochemical serotonin to initiate changes in their behavior and lifestyle.

research news

Unpacking brain damage in ALS

Researchers gain new insight into how motor neurons in the brain die during ALS

Researchers look to understand the causes of amyotrophic lateral sclerosis (ALS), in the hope of finding new ways to treat the disease. A new study published online today (December 17th) in the Cell Press journal Neuron shows that a common gene mutation in ALS generates a deadly protein that may cause the damage in the brain that leads to ALS.

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