Rhythm of breathing affects memory and fear

December 7, 2016 | Marla Paul, Northwestern University

A participant demonstrates the experimental set up with a breathing monitor and computer to display images for review. Video still.
Credit: Northwestern University

Breathing is not just for oxygen; it is also linked to brain function and behavior -

Northwestern University Feinberg School of Medicine scientists have discovered for the first time that the rhythm of breathing creates electrical activity in the human brain that enhances emotional judgments and memory recall.

These effects on behavior depend critically on whether you inhale or exhale and whether you breathe through the nose or mouth.

See Also: Tracing the scent of fear

In the study, individuals were able to identify a fearful face more quickly if they encountered the face when breathing in compared to breathing out. Individuals also were more likely to remember an object if they encountered it on the inhaled breath than the exhaled one. The effect disappeared if breathing was through the mouth.

"One of the major findings in this study is that there is a dramatic difference in brain activity in the amygdala and hippocampus during inhalation compared with exhalation," said lead author Christina Zelano, assistant professor of neurology at Northwestern University Feinberg School of Medicine. "When you breathe in, we discovered you are stimulating neurons in the olfactory cortex, amygdala and hippocampus, all across the limbic system."

The study is published in the Journal of Neuroscience. The senior author is Jay Gottfried, professor of neurology at Feinberg.

Related: EEG study findings reveal how fear is processed in the brain

Northwestern scientists first discovered these differences in brain activity while studying seven patients with epilepsy who were scheduled for brain surgery. A week prior to surgery, a surgeon implanted electrodes into the patients' brains in order to identify the origin of their seizures. This allowed scientists to acquire electro-physiological data directly from their brains. The recorded electrical signals showed brain activity fluctuated with breathing. The activity occurs in brain areas where emotions, memory and smells are processed.

Credit: Northwestern University
 

This discovery led scientists to ask whether cognitive functions typically associated with these brain areas—in particular fear processing and memory—could also be affected by breathing.

The amygdala is strongly linked to emotional processing, in particular fear-related emotions. So scientists asked about 60 subjects to make rapid decisions on emotional expressions in the lab environment while recording their breathing. Presented with pictures of faces showing expressions of either fear or surprise, the subjects had to indicate, as quickly as they could, which emotion each face was expressing.

Learn More: Maturing brain flips function of amygdala in regulating stress hormones

When faces were encountered during inhalation, subjects recognized them as fearful more quickly than when faces were encountered during exhalation. This was not true for faces expressing surprise. These effects diminished when subjects performed the same task while breathing through their mouths. Thus the effect was specific to fearful stimuli during nasal breathing only.

In an experiment aimed at assessing memory function—tied to the hippocampus—he same subjects were shown pictures of objects on a computer screen and told to remember them. Later, they were asked to recall those objects. Researchers found that recall was better if the images were encountered during inhalation.

The findings imply that rapid breathing may confer an advantage when someone is in a dangerous situation, Zelano said.

"If you are in a panic state, your breathing rhythm becomes faster," Zelano said. "As a result you'll spend proportionally more time inhaling than when in a calm state. Thus, our body's innate response to fear with faster breathing could have a positive impact on brain function and result in faster response times to dangerous stimuli in the environment."

Read Next: Researchers switch emotion linked to memory

Another potential insight of the research is on the basic mechanisms of meditation or focused breathing. "When you inhale, you are in a sense synchronizing brain oscillations across the limbic network," Zelano noted.

Note: Material may have been edited for length and content. For further information, please contact the cited source.

Northwestern University   Original reporting by: Marla Paul

Publication

Zelano C et al. Nasal Respiration Entrains Human Limbic Oscillations and Modulates Cognitive Function.  Journal of Neuroscience, Published December 7 2016. doi: 10.1523/JNEUROSCI.2586-16.2016

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